Fakultät Informatik/Mathematik

Publikationen

S. Lange, J. Schmied, P. William, A. Voss-Böhme. Minimal cellular automaton model with heterogeneous cell sizes predicts epithelial colony growth. Journal of Theoretical Biology 2024, 111882 doi.org/10.1016/j.jtbi.2024.111882
F. Franke, S. Michlíková, S. Aland, LA Kunz-Schughart, A. Voss-Böhme, S. Lange. Efficient Radial-Shell Model for 3D Tumor Spheroid Dynamics with Radiotherapy. Cancers 15(23):5645 (2023) doi.org/10.3390/cancers15235645
J. M. Nava-Sedeño, H. Hatzikirou, A. Voß-Böhme, L. Brusch, A. Deutsch, F. Peruani. Vectorial active matter on the lattice: polar condensates and nematic filaments. New J. Phys. 2023; 25(12): 1367-2630 doi: 10.1088/1367-2630/ad1498
F. Franke, S. Aland, H.J. Böhme, A. Voss-Böhme, S. Lange. Is Cell segregation just like oil and water? PLoS Comput Biol 18(9): e1010460 (2022) doi: 10.1371/journal.pcbi.1010460
S. Lange, R. Mogwitz, D. Hünniger, A. Voss-Böhme. Modeling age-specific incidence of colon cancer via niche competition. PLoS Comput Biol 18(8): e1010403 (2022) doi: 10.1371/journal.pcbi.1010403
F. M. Schwarz, I. Schniewind, M. J. Besso, S. Lange, A. Linge, S. G. Patil, S. Loeck, D. Klusa, A. Dietrich, A. Voss-Boehme, A. Nowrouzi, M. Krause, A. Dubrovska, I. Kurth, C. Peitzsch. Plasticity within aldehyde dehydrogenase-positive cells determines prostate cancer radiosensitivity. Mol Cancer Res Feb 8 (2022) doi: 10.1158/1541-7786.MCR-21-0806
P. Rossbach, H.-J. Böhme, S. Lange, A. Voss-Böhme. Model-Based Prediction of an Effective Adhesion Parameter Guiding Multi-Type Cell Segregation. Entropy 23 (11), 1378 (2021) doi:10.3390/e23111378
S. Lange, B.M. Friedrich. Network permeability changes according to a quadratic power law upon removal of a single edge. EPL 134(6): 64002 (2021) doi: 10.1209/0295-5075/134/64002
S. Lange, B.M. Friedrich. Sperm chemotaxis in marine species is optimal at physiological flow rates according theory of filament surfing. PLOS Computational Biology 17(4): e1008826 (2021) doi: 10.1371/journal.pcbi.1008826
N. Adam, F. Franke, S. Aland. A Simple Parallel Solution Method for the Navier-Stokes Cahn-Hilliard Equations. Mathematics 8(8): 1224 (2020) doi:10.3390/math8081224
A. Dirkse, A. Golebiewska, T. Buder, P. V. Nazarov, A. Muller, S. Poovathingal, N. H. C. Brons, S. Leite, N. Sauvageot, D. Sarkisjan, M. Seyfrid, S. Fritah, D. Stieber, A. Michelucci, F. Hertel, C. Herold-Mende, F.o Azuaje, A. Skupin, R. Bjerkvig, A. Deutsch, A. Voss-Böhme and S. P. Niclou. Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment. Nature Communications 10, Article number: 1787 (2019) doi:10.1038/s41467-019-09853-z
T. Buder, A. Deutsch, B. Klink, A. Voss-Böhme. Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches. Frontiers in Oncology. 8:668 (2019) doi:10.3389/fonc.2018.00668
K. Talkenberger, E. Ada Cavalcanti-Adamda, A. Voss-Böhme, A. Deutsch. Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments. Scientific Reports 7: Article number: 9237 (2017) doi:10.1038/s41598-017-09300-3
D. Reher, B. Klink, A. Deutsch, A. Voss-Böhme. Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model. Biology Direct 12:18 (2017) doi: 10.1186/s13062-017-0188-z
T. Buder, A. Deutsch, M. Seifert, A. Voss-Böhme. CellTrans: An R package to quantify stochastic cell state transitions. Bioinformatics and Biology Insights 11, 1-14 (2017) doi: 10.1177/1177932217712241
T. Buder, A. Deutsch, B. Klink, A. Voss-Böhme. Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma. PLoS Computational Biology 11(12): e1004662 (2015) doi:10.1371/journal.pcbi.1004662
K. Böttger, H. Hatzikirou, A. Voss-Böhme, E. Ada Cavalcanti-Adam, M. A. Herrero, A. Deutsch. An Emerging Allee effect is critical for tumor initiation and persistance. PLOS Computational Biology 11(9):E1004366 (2015) doi:10.1371/journal.pcbi.1004366

Konferenzbeiträge

Image segmentation of irradiated tumour spheroids by Fully Convolutional Networks. Matthias Streller (IbSB 2022, ECMTB 2022, SACB 2022)
Modeling age-specific incidence of colon cancer via niche competition. Steffen Lange (SACB 2022)
Is cell segregation just like oil and water: asymptotic versus transitory regime. Florian Franke (DPG Frühjahrstagung 2022, ECMTB 2022, SACB 2022)
Model-based prediction of an effective adhesion parameter guiding multi-type cell segregation. Philipp Roßbach (DPG Frühjahrstagung 2022, ECMTB 2022, SACB 2022)
Sperm chemotaxis in marine species is optimal at physiological flow rates according theory of filament surfing. Steffen Lange (APS March meeting 2022, WCB 2022, PHYMOT 2022)
Determination of the critical adhesion parameter for the sorting behavior of a cell system with several cell types using statistical learning methods. Philipp Roßbach (SMB 2020 Annual Meeting, DPG Frühjahrstagung 2021)
Is cell segregation just like oil and water: A phase field approach. Florian Franke (SMB 2020 Annual Meeting, DPG Frühjahrstagung 2021)
Analysis of cell contact inhibition during growth of epithelial tissue. Sebastian Rühle (SMB 2020 Annual Meeting, DPG Frühjahrstagung 2021)
Modeling initiation and progression of tumor tissue: Niches and heterogeneity. Steffen Lange (Oncoray Seminar März 2020, Steffen Löck)